GTBP Monoclonal Antibody
簡要描述:GTBP Monoclonal Antibody宿主: Monoclonal, Mouse反應性: Human應用: WB;ELISA
產品型號: YP-Ab-00068
所屬分類:單克隆抗體
更新時間:2024-11-01
詳細說明:
GTBP Monoclonal Antibody
抗體,也叫免疫球蛋白(Ig),是一種能特異性結合抗原的糖蛋白,而抗原是在易感染動物體內引發(fā)抗體產生的物質。在體內,抗體是由于外源性分子的侵襲而產生的。抗體以一個或者多個Y字形單體存在,每個Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據它們的分子量大小來命名的。Y字形結構的頂端是可變區(qū),為抗原結合部位。任何一個抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結構上的差異),每一個抗體的重鏈則決定了它的類或型。
產品詳情
GTBP Monoclonal Antibody detects endogenous levels of GTBP protein.
免疫原詳細信息
Purified recombinant fragment of human GTBP expressed in E. Coli.
相關試劑
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
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備注:圖片僅供參考。僅供科研,不可用于臨床。