NSD1 Monoclonal Antibody
簡要描述:NSD1 Monoclonal Antibody宿主: Monoclonal, Mouse反應(yīng)性: Human應(yīng)用: WB
產(chǎn)品型號: YP-Ab-00089
所屬分類:單克隆抗體
更新時間:2024-11-01
詳細(xì)說明:
NSD1 Monoclonal Antibody
抗體,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的??贵w以一個或者多個Y字形單體存在,每個Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),為抗原結(jié)合部位。任何一個抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個抗體的重鏈則決定了它的類或型。
產(chǎn)品詳情
NSD1 Monoclonal Antibody detects endogenous levels of NSD1 protein.
免疫原詳細(xì)信息
Purified recombinant human NSD1 protein fragments expressed in E.coli.
相關(guān)試劑
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
背景
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isofo
天津俊達(dá)生物科技有限公司,是從事實驗室耗材銷售的現(xiàn)代化生物科技企業(yè),公司本著“誠信為本,互利共贏"的核心價值觀,秉承“以市場為導(dǎo)向,提供服務(wù)"的宗旨為各大院校、科研單位、第三方實驗室檢測機(jī)構(gòu)等提供的產(chǎn)品和服務(wù)。目前公司主要經(jīng)營分子生物學(xué)、細(xì)胞生物學(xué)、免疫學(xué)等生物學(xué)產(chǎn)品,多種實驗室耗材 歡迎垂詢!
備注:圖片僅供參考。僅供科研,不可用于臨床。